Copper (ICP/MS) – Equine
Copper measurement using Inductively Coupled Plasma Mass Spectrometry (ICP/MS) is a precise and reliable diagnostic tool for evaluating copper levels in equines. Copper is an essential trace mineral that plays a critical role in numerous physiological processes, including connective tissue development, iron metabolism, and the formation of melanin and enzymes essential for antioxidant defense.Deficiencies in copper can lead to developmental orthopedic diseases, anemia, and poor coat pigmentation, while excessive copper intake can result in toxicity, leading to liver damage and gastrointestinal distress. The ICP/MS method provides highly sensitive and specific quantification of copper levels in serum samples, allowing veterinarians to identify imbalances and tailor dietary or medical interventions appropriately. This test is particularly valuable for horses on customized diets, in areas with known trace mineral imbalances, or presenting clinical signs of copper-related disorders.
Test name
Copper (ICP/MS) – Equine
Test Code
E110
Section
Analytical Chemistry
Species
Equine
Specimen
2 ml Serum
Collection Guidelines
- Collect an adequate amount of blood in a plain red-top tube or serum separator tube (yellow-top tube). Allow it to clot at room temperature for 30 to 60 minutes before separation.
- Centrifuge to separate the serum. Transfer the clear serum into a new, leak-proof plain red-top tube and label it as “serum.”
- Excessively hemolyzed samples are not suitable for this test.
- Unspun samples will not be accepted.
- Refrigerate sample at 4oC until shipment.
Turnaround time
14-21 days
Packing Instructions
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label. Ensure the submittal form is completed with the animal’s information and relevant medical history.
References
- Smith, M.C., et al. “The Role of Copper in Equine Health: Diagnostic and Nutritional Implications.” Journal of Equine Veterinary Science, 2021.
- Bailey, S.R., et al. “Assessment of Trace Mineral Imbalances in Horses Using ICP/MS.” Veterinary Clinics of North America: Equine Practice, 2022.
- Geor, R.J., et al. “Advances in the Diagnosis of Equine Copper Deficiency and Toxicity.” Journal of Veterinary Diagnostic Investigation, 2023.
