Insulin Autoantibody
The Insulin Autoantibody Test is a diagnostic tool used to detect autoantibodies against insulin in an animal’s blood. The presence of insulin autoantibodies may indicate an autoimmune response, commonly associated with type 1 diabetes mellitus or insulin resistance. This test is particularly useful in distinguishing autoimmune diabetes from other forms of diabetes and in assessing the potential for insulin-related complications in treated animals. By identifying insulin autoantibodies, veterinarians can better understand the underlying cause of diabetes, optimize treatment plans, and monitor therapeutic responses.
Test name
Insulin Autoantibody
Test Code
3005
Section
Endocrinology
Species
Canine and Feline
Specimen
2 ml Serum
Collection Guidelines
- Collect an adequate amount of blood in a plain red-top tube or serum separator tube (yellow-top tube). Allow it to clot at room temperature for 30 to 60 minutes before separation.
- Centrifuge to separate the serum. Transfer the clear serum into a new, leak-proof plain red-top tube and label it as “serum.”
- Excessively hemolyzed samples are not suitable for this test.
- Unspun samples will not be accepted.
- Refrigerate sample at 4oC until shipment.
Turnaround time
14-21 days
Packing Instructions
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label. Ensure the submittal form is completed with the animal’s information and relevant medical history.
References
- Hoenig, M., et al. (2023). “Autoimmune Diabetes in Companion Animals: Diagnostic and Therapeutic Considerations.” Veterinary Clinics of North America: Small Animal Practice.
- Hess, R.S., et al. (2022). “Advances in Autoantibody Testing for Diabetes in Veterinary Medicine.” Journal of Veterinary Diagnostic Investigation.
- Davison, L.J., et al. (2021). “Immune-Mediated Diabetes in Dogs and Cats: Current Perspectives.” Journal of Small Animal Practice.
