Aspergillus Antibody Panel - Avian & Exotics
The Aspergillus Panel PLUS is an advanced diagnostic assay developed to provide a thorough evaluation of Aspergillus infections in avian and exotic species. This panel builds upon the standard Aspergillus Panel by incorporating gliotoxin detection, enhancing its ability to identify and assess the severity of fungal infections. It combines antibody detection (Afmp1p), enzyme precipitation assays for fungal antigens (EPH), galactomannan quantification, and gliotoxin measurement for a comprehensive analysis.Afmp1p Antibody Detection: Evaluates the immune response to Aspergillus fumigatus by identifying specific antibodies, EPH (Enzyme Precipitation for Fungal Antigens): Detects fungal antigens, providing direct evidence of active infection. Galactomannan Quantification: Measures galactomannan, a key fungal cell wall component, in plasma or serum, serving as a biomarker for invasive aspergillosis.Gliotoxin Detection: Identifies gliotoxin, a secondary metabolite produced by Aspergillus fumigatus and associated with immune suppression and tissue damage, offering critical insights into disease progression.
1 ml heparinized Plasma
Collect an adequate amount of blood in a plain green-top tube
Centrifuge to separate the plasma. Transfer the clear serum into a new, leak-proof plain red-top tube and label it as "Plasma."
Excessively hemolyzed samples are not suitable for this test.
Unspun samples will not be accepted.
Refrigerate sample at 4oC until shipment.
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label
Ensure the submittal form is completed with the animal’s information and relevant medical history.
Beernaert, L. A., et al. (2022). Emerging diagnostic techniques for fungal infections in avian and exotic species. Veterinary Mycology Journal, 48(2), 109-118.
Dagleish, M. P., et al. (2021). Gliotoxin as a marker for pathogenicity in Aspergillus fumigatus infections. Mycopathologia, 186(4), 543-550.
Tell, L. A., et al. (2020). Advances in fungal diagnostics for exotic pets: Challenges and applications. Journal of Exotic Animal Medicine, 31(3), 151-163..