Digital Copper Quantification
Quantification of copper in stained tissue slides involves assessing copper levels in formalin-fixed, paraffin-embedded (FFPE) liver tissue sections. This is achieved through Digital Copper Quantification (DCQ), a specialized technique that quantifies copper deposition in stained slides. DCQ is exclusively performed on liver biopsies submitted for liver consultations or as part of routine histopathology. The interpretation of results requires correlation with the distribution of copper in the tissue and its association with pathological features such as inflammation, degeneration, and fibrosis.
One of the following: fixed tissue in 10% formalin, paraffin embedded tissue, or 3 unstained formalin-fixed tissue sections on positively charged slides. Slide preparation using submitted tissue will incur additional charge.
Tissue: Samples must be submitted in sealed, leak-proof, wide-mouth plastic containers. Glass containers are not acceptable and will incur an additional processing fee
Slides: Samples should be submitted in designated slide container
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label
Ensure the submittal form is completed with the animal’s information and relevant medical history.