Epilepsy Therapeutic Panel

The Epilepsy Therapeutic Panel is a comprehensive diagnostic tool designed to monitor and manage epilepsy treatment in veterinary patients. This panel quantifies the serum concentrations of key antiepileptic drugs, including Bromide (measured by UV/Vis spectrophotometry), Levetiracetam (analyzed using Liquid Chromatography-Mass Spectrometry, LC/MS), Phenobarbital (via LC/MS), and Zonisamide (via LC/MS). The panel enables precise therapeutic drug monitoring (TDM), ensuring efficacy while minimizing toxicity.

5 ml Serum

• Collect an adequate amount of blood in a plain red-top tube or serum separator tube (yellow-top tube). Allow it to clot at room temperature for 30 to 60 minutes before separation.

• Centrifuge to separate the serum. Transfer the clear serum into a new, leak-proof plain red-top tube and label it as "serum."

• Excessively hemolyzed samples are not suitable for this test.

• Unspun samples will not be accepted.

• Refrigerate sample at 4oC until shipment.

• Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label

• Ensure the submittal form is completed with the animal’s information and relevant medical history.

1. Trepanier, L. A., & Van Schoick, A. (2021). Monitoring Antiepileptic Drugs in Veterinary Medicine: Current Practices and Future Directions. Journal of Veterinary Internal Medicine, 35(4), 1421–1430.

2. Podell, M., Volk, H. A., & Berendt, M. (2016). 2015 ACVIM Small Animal Consensus Statement on Seizure Management in Dogs. Journal of Veterinary Internal Medicine, 30(2), 477–490.

3. Packer, R. M. A., & Volk, H. A. (2015). Epilepsy in Companion Animals: A Comparative Review of the Impact on the Owner and the Animal. Veterinary Record, 177(8), 203–209.

Test Code

8024

Section

Analytical Chemistry

Species

Canine, Feline

Specimen

Turnaround Time

Contact Vettto Team

Collection Guidelines

Packaging Instructions

References