Melanoma Panel - Complete (IHC)
The Complete Melanoma Panel is an advanced diagnostic tool designed to evaluate and prognosis of melanoma in canines. This panel includes a comprehensive set of immunohistochemical markers: Melan A, PNL-2, and a cocktail of TRP-1 and TRP-2, which are essential for identifying melanocytic origin. Additionally, it includes analysis of cellular proliferation activity through Ki-67 immunohistochemistry (IHC), providing critical insights into tumor aggressiveness and progression potential.
Section
Cancer Diagnostics
Test Code
1008
One of the following: fixed tissue in 10% formalin, paraffin embedded tissue, or 3 unstained formalin-fixed tissue sections on positively charged slides. Slide preparation using submitted tissue will incur additional charges.
Tissue: Samples must be submitted in sealed, leak-proof, wide-mouth plastic containers. Glass containers are not acceptable and will incur an additional processing fees.
Slides: Samples should be submitted in designated slide containers.
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label.
Ensure the submittal form is completed with the animal’s information and relevant medical history.
Smedley, R.C., et al. "Diagnostic Utility of Melan A, PNL-2, and TRP Markers in Canine Melanomas." Veterinary Pathology, 2021.
Medleau, L., et al. "Evaluating Ki-67 as a Prognostic Marker in Veterinary Melanomas." Journal of Veterinary Diagnostic Investigation, 2022.
Kosovsky, B., et al. "Immunohistochemical Markers in Melanoma: Use in Prognosis and Therapy." Veterinary Clinics of North America: Small Animal Practice, 2023.