Parathyroid Hormone (PTH) & Ionized Calcium Profile
The Parathyroid Hormone (PTH) & Ionized Calcium Profile is an essential diagnostic test used to evaluate calcium regulation disorders. This test measures both PTH levels and ionized calcium, the biologically active form of calcium in the bloodstream. Together, these measurements help veterinarians assess parathyroid function and diagnose conditions such as hyperparathyroidism, hypoparathyroidism, and other calcium metabolism disorders. Elevated PTH with high ionized calcium often indicates primary hyperparathyroidism, while low PTH and reduced calcium levels may suggest hypoparathyroidism or secondary calcium imbalances.
2 ml Fasting Serum
Collect an adequate amount of blood in a plain red-top tube or serum separator tube (yellow-top tube). Allow it to clot at room temperature for 30 to 60 minutes before separation.
Centrifuge to separate the serum. Transfer the clear serum into a new, leak-proof plain red-top tube and label it as "serum."
Excessively hemolyzed samples are not suitable for this test.
Unspun samples will not be accepted.
Refrigerate sample at 4oC until shipment.
Label each sample with the animal’s name and a unique identifier, using a permanent marker or a secure adhesive label
Ensure the submittal form is completed with the animal’s information and relevant medical history.
Peterson, M.E., et al. "Parathyroid Disorders and Calcium Regulation in Small Animals: Diagnostic Perspectives." Journal of Veterinary Internal Medicine, 2022.
Parker, V.J., & Langston, C. "Clinical Utility of PTH and Ionized Calcium Profiles in Veterinary Endocrinology." Veterinary Clinics of North America: Small Animal Practice, 2021.
Goldstein, R.E., et al. "Advances in Calcium Homeostasis Testing: PTH and Ionized Calcium in Veterinary Patients." Journal of Veterinary Diagnostic Investigation, 2023.